Dr. David Y. Graham is a gastroenterologist at the Baylor College of Medicine in Houston, TX. Here, he details a long term study conducted on Crohn’s disease incidence in the Kingdom of Bahrain. Over time, the rate of Crohn’s disease increased significantly from 4.8 cases per 100,000 to 8.0 cases per 100,000. PCR (IS900 series) testing for MAP DNA in Crohn’s patients revealed that 76.7% were positive after 1 test, but when the researchers repeated the test up to 4 times, 100% of the Crohn’s patients eventually tested positive for MAP DNA. Imported beef and dairy may provide an explanation for the increase in disease.
2017 MAP Conference | Detection of MAP in Dairy Products, and Novel MAP Detection Methods with Potential Application to Blood Testing
Dr. Irene Grant is a Senior Lecturer in Microbiology and Food Safety at Queen’s University, Belfast Ireland. In her presentation, she explains and contrasts a variety of methods for detecting MAP in milk, details the latest advances from her lab including PMS-phage assay. which detects higher levels of MAP in milk and infant formula. Discussion of how PMS-phage assay for MAP could be applied to human blood samples and a Q&A session follows.
The MAP Gap Newsletter | April 2017
Human Paratuberculosis Foundation is dedicated to providing the most up-to-date information in our field to assist patients around the world in making informed decisions about their treatment. We are grateful for the support of this community and look forward to taking this journey together.
Read all the latest news and research about Mycobacterium avium subsp. paratuberculosis (MAP) and the treatment of Crohn’s and other diseases using AMAT therapy. Enjoy!
2017 MAP Conference | Treating MAP in Crohn’s Disease
Prof. Thomas Borody is a gastroenterologist who is the founder and Medical Director of the Centre for Digestive Diseases in Sydney, Australia. He has established novel therapies in gastrointestinal areas such as Inflammatory Bowel Disease, Irritable Bowel Syndrome, Parasite infestation, Resistant Helicobacter pylori and C. difficile. In this presentation, he discusses how he treats MAP-driven Crohn’s disease, treatment for fistulae, the synergy of infliximab and antibiotics, and antibiotics in treatment-naive patients. Anti-MAP therapy for pyoderma gangrenosum is also briefly discussed. A group of patients have long-term, medication free remission due to Anti-MAP therapy.
2017 MAP Conference | The Rationale for Antibiotics in Crohn’s Disease
Dr. Shafran is a gastroenterologist who has been practicing in the Orlando area since 1979. He has used Anti-MAP therapy as part of his practice, and talks about his experience treating patients, including why current therapies have no role in treating Crohn’s disease in his opinion. Research from Crohn’s patients who have been treated with antibiotics is presented. Deep mucosal healing and sustained remission was found in 11 patients over an 18 year period.