2018 Berkeley

Berkeley Conference | Case Report: Chronic neurologic and psychiatric illness in a patient with atypical Mycobacteria

Berkeley Conference | Case Report: Chronic neurologic and psychiatric illness in a patient with atypical Mycobacteria

Here, Dr. Harry Oken presents the case of a middle-aged patient with a history of depression and hypothyroidism who had unusual symptoms, including one-sided allodynia, “pins and needles” sensation, headaches, joint pain, periodic night sweats and IBS symptoms. Treatments included a therapeutic trial of steroids, which caused a steroid psychosis and led to inpatient psychiatric hospitalization, culminating in 25+ Electroconvulsive treatments. A blood culture was positive for an atypical Mycobacteria and a three drug antibiotic regimen was begun with dramatic sustained improvement.

Berkeley Conference | From Achilles’ heel to a peptide-based vaccine for Mycobacterium	paratuberculosis

Berkeley Conference | From Achilles’ heel to a peptide-based vaccine for Mycobacterium paratuberculosis

In this presentation, Dr. Gaber Abdellrazek, a postdoctoral fellow who is currently researching the pathogenic mechanism of MAP with Dr. William Davis, explains their lab’s latest findings. They have discovered that the deletion of a single gene cripples Map’s ability to establish a persistent infection. This led to the discovery of a peptide with potential for development as a vaccine. Studies with the peptide in tissue culture show vaccination leads to development of immune cells that can kill Map inside macrophages, an essential requirement for a vaccine against intracellular pathogens. While this is being investigated in cattle, it could have implications for human health as well.

Berkeley Conference | Preliminary Findings of the MAP/Crohn’s Disease Testing Study

Berkeley Conference | Preliminary Findings of the MAP/Crohn’s Disease Testing Study

Dr. J. Todd Kuenstner reports preliminary results of the MAP/Crohn’s disease testing study, which found that viable MAP organisms were detected by phage assay in 54.6% of the 194 subjects in the study. The study will remain blinded until March 2019, when all testing is complete. Publication is expected in July 2019.

Thank you to everyone who has made this study possible. To all of the Crohn’s and control subject participants, to the researchers who have donated their time and expertise, and to our Human Para community who have donated time and resources to this endeavor. A special note of thanks to Valerie Joly of Crohn’s Warrior Fights and the Denver, NC community for hosting a golf tournament which raised a whopping $22,678.32, and funded the majority of the study. We couldn’t have done it without all of you!

Berkeley Conference | Two Case Reports: Differing Antibiotic Regimens Resulting in Long-Term Mucosal Healing in Pediatric and Adult Crohn’s Patients

Berkeley Conference | Two Case Reports: Differing Antibiotic Regimens Resulting in Long-Term Mucosal Healing in Pediatric and Adult Crohn’s Patients

In this presentation, Dr. William Chamberlin describes two Crohn’s disease patients who have found long term healing. The first, an adult patient, has altered the traditional antibiotic regimen to avoid side effects and keep the disease in deep remission. The second is a 10 year old pediatric patient who experienced remarkable healing on an antibiotic regimen.

Berkeley Conference | Qu Biologics’ Goal: Curing Crohn’s Disease by Restoring Innate Immunity

Berkeley Conference | Qu Biologics’ Goal: Curing Crohn’s Disease by Restoring Innate Immunity

Dr. Hal Gunn is the founder and CEO of Qu Biologics, and has dedicated his professional life to understanding how to optimally support the body’s immune response to chronic disease. Dr. Gunn is recognized both nationally and internationally as a leader in the field of supportive cancer care, and is the founder and past-CEO of InspireHealth, Canada’s leading supportive oncology centres. Dr. Gunn obtained his Doctorate of Medicine from the University of British Columbia and remains on faculty at UBC’s School of Medicine. To learn more about QBECO and the study, please click on this link: https://www.quibd.com/

Berkeley Conference | Phase Assay Testing of Human PBMC’s

Berkeley Conference | Phase Assay Testing of Human PBMC’s

Dr. Irene Grant is a Professor of Microbiology and Food Safety at Queen’s University in Belfast.  Her long time research interest has been Mycobacterium avium subsp. paratuberculosis, its heat resistance, presence in milk and dairy products, and methods for its accurate detection and enumeration. She has published extensively on this subject and is recognized as an international authority on this potentially foodborne and zoonotic bacterium.

In this presentation, Dr. Grant reports on some preliminary findings of the Crohn’s/MAP Testing Study funded by Human Para, and describes her phage assay technique used for the detection of MAP.

Berkeley Conference | The Development and validation of a novel biomarker for diagnosis of Inflammatory Bowel Disease

Berkeley Conference | The Development and validation of a novel biomarker for diagnosis of Inflammatory Bowel Disease

John Aitken is a free-lance microbiologist based out of Christchurch, New Zealand and the senior director of Otakaro Pathways, Ltd. Prior to his current position, he worked in medical microbiology for public and private providers for more than 40 years. His particular areas of interest are antimicrobial resistance and emerging bacterial infectious diseases. John is presently involved in research surrounding the relationship between immune diseases and the Mycobacterium species.

Here, John discusses his latest research into mycobacterium species found in Crohn’s disease patients.

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