Dr. Nicole Parrish of the Johns Hopkins School of Medicine and Dr. Neil Goldberg of the University of Maryland, begin the presentation by discussing tuberculosis and the Wayne Model of Non-Replicating persistence, and how that model relates to MAP latency. Their research shows that MAP can convert from an aerobic (oxygen using) state to an anaerobic (non-oxygen) state similar to that seen in tuberculosis. The presentation concludes with a discussion of MAP antibiotic susceptibility and a case study where a combination of antibiotics led to cessation of Crohn’s disease and pyoderma gangrenosum.
Dr. C. Thomas Dow | All Roads Lead from Crohn’s
“All roads lead to Rome” is the old axiom that described the central place the city of Rome played in its millennial world empire. All roads lead from Crohn’s – this narrative discusses human diseases associated with Mycobacterium avium subsp. paratuberculosis (MAP) other than Crohn’s disease, including Blau syndrome, Type I diabetes, sarcoidosis, lupus and Parkinson’s disease. For our purposes these roads are trails; genetic trails.
The MAP Gap Newsletter | July 2017
Human Paratuberculosis Foundation is dedicated to providing the most up-to-date information in our field to assist patients around the world in making informed decisions about their treatment. We are grateful for the support of this community and look forward to taking this journey together.
Read all the latest news and research about Mycobacterium avium subsp. paratuberculosis (MAP) and the treatment of Crohn’s and other diseases using Anti-MAP therapy. Enjoy!
2017 MAP Conference | Introduction
In these first two videos, Dr. Behr and Dr. Chamberlin introduce the conference, frame the issue of MAP and address the issue of causality.
2017 MAP Conference | MAP: A Zoonotic Pathogen
Dr. Collins gives an overview of MAP from a veterinary perspective, including where MAP is found in the environment, hallmarks of MAP infections in cows and other animals and detection methods. Contamination of MAP in food products and human exposure vehicles are discussed alongside solutions which can be implemented to stop the spread of MAP.