Posts by: Moderator

Joint MAP Testing Project

Human Paratuberculosis Foundation seeks to sponsor innovative research projects which will add to our understanding of MAP’s role in human disease. We encourage cooperative efforts among investigators, research centers, and other resources. Human Para is pleased to announce our first research project in conjunction with 10 investigators from 5 different countries. This initial study seeks to confirm that Crohn’s disease patients have a significantly higher rate of MAP infection than individuals that do not have Crohn’s, and to compare more recent rapid culture methods from multiple laboratories. Our funding goal is $40,000 which will allow 210 samples (60 from Crohn’s patients, 150 controls) to be tested. MAP cultures and antibody studies will be performed in the laboratories of John Aitken, Timothy Bull, Irene Grant, Horacio Bach, Peilin Zhang and Raghava Potula.

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To People with Crohn’s Disease

by Judith Eve Lipton, MD originally published June 7, 2015, revised October 24, 2017 I receive many letters from people around the world asking about treating Crohn’s disease with antibiotics, under the theory that Crohn’s disease is an infection caused by MAP, Mycobacterium avium subspecies paratuberculosis. I am a psychiatrist, not a gastroenterologist (GI), and not qualified to make specific suggestions about treating Crohn’s disease. I never treat any GI patients myself, and never did. I will never tell people specific doses or protocols for treating MAP because every patient is different. If you elect to learn more and follow this path, you will need your own local physician. I am only offering general information.

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The MAP Gap Newsletter | October 2017

Read all the latest news and research about Mycobacterium avium  subsp. paratuberculosis (MAP) and the treatment of Crohn’s and other MAP-driven diseases. Human Paratuberculosis Foundation is dedicated to providing the most up-to-date MAP information to assist healthcare professionals and patients around the world to make informed decisions about their treatment. We are grateful for the support of this community and look forward to taking this journey together.

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Consensus Article from the 2017 MAP Conference

Human Para is pleased to share the consensus article from the 2017 MAP conference in Philadelphia. This effort represents a historic collaboration of the world’s experts on Mycobacterium avium spp. paratuberculosis (MAP), who are concerned about the impact of MAP on human health. The goal of this collaboration is to advance better treatment options for patients suffering from MAP-driven conditions.

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Fight for the Cure Golf

Crohn’s Warrior Valerie Joly and Verdict Ridge Golf and Country Club will be hosting a Fight for the Cure Golf Tournament on May 17, 2018 All proceeds will benefit Human Para in their quest to fund innovative research into MAP-driven diseases.

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Events

Upcoming Events September 21 & 22, 2018 Mycobacterial Implications in Crohn's and Chronic Inflammatory Diseases Berkeley, California We are pleased to announce that Human Paratuberculosis Foundation will be hosting a MAP-focused conference at the Lawrence Hall of Science at UC Berkeley on September 21 & 22, 2018. This event will feature presentations and updates from ...

Educational Pack for Patients

Human Paratuberculosis Foundation has created an information pack designed with patients in mind. This downloadable pack, containing links to the latest research and resources on MAP science, can be printed or sent in electronic format. Presented in a brief, easy to read format, it provides an introduction to MAP in Crohn’s and other diseases, discusses detection rates, and sets out therapeutic options including clinical trials. A full page of additional resources follows, concluding with a short synopsis about the Human Para organization. This can be used to help you prepare to get the most out of your next visit with your healthcare professional. Understanding your condition and the latest research can increase your chances of improving and maintaining your health.

Request for Research Proposals

Human Paratuberculosis Foundation is pleased to announce that it is seeking research proposals from qualified applicants that will advance our knowledge about the role that Mycobacterium avium spp. paratuberculosis (MAP) plays in human disease. MAP has been detected in significantly higher numbers in patients with Crohn’s disease, Type 1 Diabetes, Multiple Sclerosis, Sarcoidosis, Hashimoto’s Thyroiditis and Psoriasis, and emerging research indicates that MAP may be involved in other conditions such as Parkinson’s disease, Blau Syndrome, Rheumatoid Arthritis and Lupus. It has been shown that patients with these conditions have genetic vulnerabilities which may hinder the immune system’s ability to correctly recognize pathogens, predisposing them to bacteria such as MAP. Human Para now seeks to sponsor innovative research projects which will add to our understanding of MAP’s role in human disease. For further details and instructions on how to submit a proposal, please see the Application Instructions.

MAP: In vitro Adaptation to Anaerobiosis, Differential Susceptibility to Antibiotics, and Implications for Therapy

Dr. Nicole Parrish of the Johns Hopkins School of Medicine and Dr. Neil Goldberg of the University of Maryland, begin the presentation by discussing tuberculosis and the Wayne Model of Non-Replicating persistence, and how that model relates to MAP latency. Their research shows that MAP can convert from an aerobic (oxygen using) state to an anaerobic (non-oxygen) state similar to that seen in tuberculosis. The presentation concludes with a discussion of MAP antibiotic susceptibility and a case study where a combination of antibiotics led to cessation of Crohn’s disease and pyoderma gangrenosum.

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Dr. C. Thomas Dow | All Roads Lead from Crohn’s

“All roads lead to Rome” is the old axiom that described the central place the city of Rome played in its millennial world empire.  All roads lead from Crohn’s – this narrative discusses human diseases associated with Mycobacterium avium subsp. paratuberculosis (MAP) other than Crohn’s disease, including Blau syndrome, Type I diabetes, sarcoidosis, lupus and Parkinson’s disease. For our purposes these roads are trails; genetic trails.

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