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Expert Review: Crohn’s MAP Vaccine May 2019 Research Paper

Expert Review: Crohn’s MAP Vaccine May 2019 Research Paper

In this article, Dr. Tim Bull breaks down the recently released journal paper from the Crohn’s MAP Vaccine organization, entitled Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored VaccineThis paper describes the initial safety studies in humans of a vaccine that is designed to stimulate immune recognition of specific components of the MAP bacterium. Dr. Tim Bull is a Reader in Infectious Diseases at St George’s, University of London. He is an internationally recognized expert in mycobacterial diseases and has over 20 years experience in working with culturing mycobacteria. He was instrumental in the initial design and development of the original vaccine and testing the efficacy of a prime-boost version in animals with MAP infection.

The MAP Gap Newsletter | April 2019

The MAP Gap Newsletter | April 2019

Human Paratuberculosis Foundation is dedicated to providing the most up-to-date information in our field to assist patients around the world in making informed decisions about their treatment. We are grateful for the support of this community and look forward to taking this journey together. Read all the latest news and research about mycobacteria, particularly Mycobacterium avium subsp. paratuberculosis (MAP), and the treatment of Crohn’s and immune disease with AMAT and other innovative therapies. Enjoy!

John Aitken | The Circle Widens

John Aitken | The Circle Widens

In his latest article, John Aitken of Otakaro Pathways describes how they have identified bacteriological aspects of Crohn’s patients and some sarcoidosis patients that are not seen in healthy controls. A case study of a patient who recovered from cardiac sarcoidosis using antibiotic treatment is discussed, as is a 2019 trial. Take-aways detailing the activity of cell wall deficient mycobacteria in sarcoidosis included!

The MAP Gap Newsletter | January 2019

The MAP Gap Newsletter | January 2019

Human Paratuberculosis Foundation is dedicated to providing the most up-to-date information in our field to assist patients around the world in making informed decisions about their treatment. We are grateful for the support of this community and look forward to taking this journey together. Read all the latest news and research about mycobacteria, particularly Mycobacterium avium subsp. paratuberculosis (MAP), and the treatment of Crohn’s and immune disease with AMAT and other innovative therapies. Enjoy!

Berkeley Conference | Case Report: Chronic neurologic and psychiatric illness in a patient with atypical Mycobacteria

Berkeley Conference | Case Report: Chronic neurologic and psychiatric illness in a patient with atypical Mycobacteria

Here, Dr. Harry Oken presents the case of a middle-aged patient with a history of depression and hypothyroidism who had unusual symptoms, including one-sided allodynia, “pins and needles” sensation, headaches, joint pain, periodic night sweats and IBS symptoms. Treatments included a therapeutic trial of steroids, which caused a steroid psychosis and led to inpatient psychiatric hospitalization, culminating in 25+ Electroconvulsive treatments. A blood culture was positive for an atypical Mycobacteria and a three drug antibiotic regimen was begun with dramatic sustained improvement.