Blog

AMAT: Together We Are Stronger

TogetherOn June 14, 2016, the journal Gut Pathogens released a new study entitled “RHB-104 Triple Antibiotics Combination in Culture is Bactericidal and Should be Effective for Treatment of Crohn’s Disease Associated with Mycobacterium paratuberculosis.” The researchers from the University of Central Florida (including Dr. Saleh Naser) found that the raw active ingredients used in RHB-104 worked together in combination to inhibit the growth of 16 Mycobacterium avium paratuberculosis (MAP) strains and 19 other mycobacterial species.

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Dietzia: A Potential Probiotic Therapy for Crohn’s Disease

Dr. Robert E. Click
Dr. Robert E. Click
In this age of organic food, chemical free products, farmer’s markets and going green, it’s no wonder that Dietzia spp. C79793-74 is generating great interest among Crohn’s disease patients. After all, if this emerging probiotic therapy could curtail the symptoms of Crohn’s disease as well as, or even better than, conventional therapies but without the side effects, it may well become the future of Crohn’s treatment. While human research and trials need to be completed, Dietzia has shown promise in cattle infected with Johne’s disease. With new information emerging about this bacterial species, we thought our readers would enjoy this timely overview. We are honored to introduce the man who discovered benefits of Dietzia spp. C79793-74, Dr. Robert E. Click.

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The MAP Gap Newsletter | April 2016

TCI BannerThe Crohns Infection is dedicated to providing the most up-to-date information in our field to assist patients around the world in making informed decisions about their treatment. We are grateful for the support of this community and look forward to taking this journey together. Here are some of the most recent developments in the area of MAP related Crohn’s Research. Enjoy!

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Gilles R. G. Monif, M.D. | How MAP Becomes Crohn’s Disease

DairyAny claim for causation of Crohn’s disease must address four key issues:

  1. Why the sudden onset of disease in the twentieth century;
  2. Why its epidemic spread;
  3. Why limited sites of involvement within the gastrointestinal tract; and
  4. Why the significant variability with respect to the age of onset.
Dr. Monif addresses these questions and more in this opinion piece published with permission of The International Association for Paratuberculosis.

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John Aitken | Endophytes

LeavesIn the plant world, endophytes exist within plants to perform essential functions in the plant – stimulation of plant immunity, competitive inhibition (making sure there is no room left for an invader) and production of chemicals capable of killing other bacteria (antibiotics). This is a process called “symbiosis.” Symbiosis occurs when two organisms co-exist and one, or both, organisms benefit from the relationship. In plants, endophytes have evolved to be part of the growth mechanisms of the plant. They are found in the roots and in the leaves. What has this to do with Crohn’s disease?

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Gilles R. G. Monif, M.D. | Understanding Crohn’s Disease

DairyA governing principle within the doctrines of international law on food safety is reflected in the words “The importance of the precautionary measures should not be played down on the grounds that the risk is not proven.” The collateral damage from not adhering to the precautionary principle is partially reflected in the numbers. In 1998, the number of Crohn’s disease afflicted individuals numbered 358,000. In 2006, this number was 560,000. In 2010, it was an estimated 800,000. In 2015, crude estimates place the figure above a million. The 2015 expanded Hruska Postulate states that Crohn’s disease is the interaction of two immune responses to MAP occurring in different time frames. Learn more about these two immune responses and welcome our newest presenter, Gilles R. G. Monif, M.D.

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